Guillermo Rodriguez
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Tutorial Article
The treatment of diarrhoea in the adult horse
R. J. Naylor* and B. Dunkel
EQUINE VETERINARY EDUCATION
Equine vet. Educ. (2009) 21 (9) 494-504
Summary
The priority in treating the equine patient with acute
diarrhoea is to stabilise the haemodynamic aberrations
secondary to the fluid and electrolyte losses. Once this has
been initiated and the patient is stabilised ancillary
treatments may be beneficial. Besides the well established
effects of NSAIDs and polymixin B on systemic
inflammation, recent studies suggest that the use of DTOS
to bind bacterial toxins and Saccharomyces boulardii to
reduce the severity and duration of diarrhoea may be
beneficial. The justification for using probiotic products is
scant. There is no evidence to suggest that systemic use of
antimicrobials benefits equine patients with colitis, with the
exception of metronidazole in cases of clostridial
diarrhoea. In light of their potentially detrimental effects,
their use can, in the opinion of the authors, not be
advocated. Better understanding of the pathways of
systemic inflammation and more selective antiinflammatory
drugs may be of great benefit in the future.
http://www.mediafire.com/?16jbbvz5s3z12hx
The treatment of diarrhoea in the adult horse
R. J. Naylor* and B. Dunkel
EQUINE VETERINARY EDUCATION
Equine vet. Educ. (2009) 21 (9) 494-504
Summary
The priority in treating the equine patient with acute
diarrhoea is to stabilise the haemodynamic aberrations
secondary to the fluid and electrolyte losses. Once this has
been initiated and the patient is stabilised ancillary
treatments may be beneficial. Besides the well established
effects of NSAIDs and polymixin B on systemic
inflammation, recent studies suggest that the use of DTOS
to bind bacterial toxins and Saccharomyces boulardii to
reduce the severity and duration of diarrhoea may be
beneficial. The justification for using probiotic products is
scant. There is no evidence to suggest that systemic use of
antimicrobials benefits equine patients with colitis, with the
exception of metronidazole in cases of clostridial
diarrhoea. In light of their potentially detrimental effects,
their use can, in the opinion of the authors, not be
advocated. Better understanding of the pathways of
systemic inflammation and more selective antiinflammatory
drugs may be of great benefit in the future.
http://www.mediafire.com/?16jbbvz5s3z12hx