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West Nile Encephalitis Virus Infection (Viral Pathogenesis and the Host Immune Response)
Editor: Michael S. Diamond
ISBN: 978-0-387-79839-4
e-ISBN: 978-0-387-79840-0
DOI: 10.1007/978-0-387-79840-0
Library of Congress Control Number: 2008940591
Springer 2009
479 Pages
7.3 MB
The aim of this book was to assemble an up-to-date and cutting edge anthology from the leading experts in the field. The chapters are balanced by submissions from newcomers who have made significant recent contributions with those from established investigators who have dedicated their careers to the study of West Nile virus. The topics are directed at the biology of West Nile virus, and cover ecology, vertebrate biology, epidemiology, clinical disease, pathogenesis, host immune response, structural biology, immune evasion, and progress on the development of vaccines and therapeutics. Nonetheless, because it belongs to a family of clinically relevant arthropod-borne human pathogens including dengue virus, Japanese encephalitis virus, yellow fever virus, and tick-borne encephalitis virus, many of the paradigms established for West Nile virus will be relevant for the transmission and pathogenesis of these viruses. Reciprocally, advances with other flaviviruses have
influenced our understanding of the West Nile pathogenesis. As such, in some sections, chapters address West Nile virus biology in the context of findings with other pathogenic flaviviruses.
Editor: Michael S. Diamond
ISBN: 978-0-387-79839-4
e-ISBN: 978-0-387-79840-0
DOI: 10.1007/978-0-387-79840-0
Library of Congress Control Number: 2008940591
Springer 2009
479 Pages
7.3 MB
The aim of this book was to assemble an up-to-date and cutting edge anthology from the leading experts in the field. The chapters are balanced by submissions from newcomers who have made significant recent contributions with those from established investigators who have dedicated their careers to the study of West Nile virus. The topics are directed at the biology of West Nile virus, and cover ecology, vertebrate biology, epidemiology, clinical disease, pathogenesis, host immune response, structural biology, immune evasion, and progress on the development of vaccines and therapeutics. Nonetheless, because it belongs to a family of clinically relevant arthropod-borne human pathogens including dengue virus, Japanese encephalitis virus, yellow fever virus, and tick-borne encephalitis virus, many of the paradigms established for West Nile virus will be relevant for the transmission and pathogenesis of these viruses. Reciprocally, advances with other flaviviruses have
influenced our understanding of the West Nile pathogenesis. As such, in some sections, chapters address West Nile virus biology in the context of findings with other pathogenic flaviviruses.
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